Diagnosed with cadaan gene mutation disease

[Boomer]

I was just diagnosed with gene mutation related to iron problem or something. I carry a copy of a gene called h63d. I got the diagnosis after doctor ordered a genetic test after my blood results showed elevated iron and saturation. My doctor straight up said this aint African disease chief.
Make sense of this for me reer dna.

 

[Aurelian]

I was just diagnosed with gene mutation related to iron problem or something. I carry a copy of a gene called h63d. I got the diagnosis after doctor ordered a genetic test after my blood results showed elevated iron and saturation. My doctor straight up said this aint African disease chief.
Make sense of this for me reer dna.

Where from Somalia you are from ?

 

[Aurelian]

The gene is mostly in Europe, rare in Africa and East Asia, but it is prominent in South Asians as well

Europeans 17-27%
South Asians 7-17%

Asians and Africans 1-3%


So, in theory you could be one of the very unlucky Africans who got that disease, or you could have some South Asians in you.

 

[The truth seeker]

May Allah cure you sxb

 

[The alchemist]

The average Somali HLA profile can look different from what doctors class as typical "African," usually coded along West African-related ancestry (WA + Bantu). The dearth of research undertaken makes it hard to estimate the frequency among Somalis. It's not unrealistic to assume cases a bit higher than South African Bantus that were studied, narrowly ranging between the tail beginning of nill-to-rare cases.

It seems you have a heterozygous allele (one gene and one copy); am I right to speculate it is a mild condition?

May you get better, inshallah. I read that one can keep age-dependent accumulated disease problems at bay during the pre-clinical period via venesection through blood extraction until one sees normal iron levels affording a normal life span. Is that what your doctor is looking for if you have hemochromatosis?

 

[Boomer]

Where from Somalia you are from ?

I am Ogaden. Mom is from Gedo(her parents from Galbeed) while my dad is from Galbeed.

 

[Boomer]

May Allah cure you sxb

Thank you wll!

 

[Boomer]

The gene is mostly in Europe, rare in Africa and East Asia, but it is prominent in South Asians as well

Europeans 17-27%
South Asians 7-17%

Asians and Africans 1-3%


So, in theory you could be one of the very unlucky Africans who got that disease, or you could have some South Asians in you.

My brother did his dna a while back and it came back like 97.5 % somali with the rest being Ethiopian and Eritrean so i am sure there’s no Asian in us.

 

[Boomer]

The average Somali HLA profile can look different from what doctors class as typical "African," usually coded along West African-related ancestry (WA + Bantu). The dearth of research undertaken makes it hard to estimate the frequency among Somalis. It's not unrealistic to assume cases a bit higher than South African Bantus that were studied, narrowly ranging between the tail beginning of nill-to-rare cases.

It seems you have a heterozygous allele (one gene and one copy); am I right to speculate it is a mild condition?

May you get better, inshallah. I read that one can keep age-dependent accumulated disease problems at bay during the pre-clinical period via venesection through blood extraction until one sees normal iron levels affording a normal life span. Is that what your doctor is looking for if you have hemochromatosis?

Yes it’s just one copy but man my symptoms were pretty devastating. From severe brain fog to 24 hour liver pain. My liver function also showed elevated numbers and I have never had a drink in my life. Doctors were surprised to see such severe symptoms with only one copy. I have been put on regular blood removal schedule and it’s helping alhamdulilah.
they think this mutation developed in the celtic lande, but as usual cadaans don’t invest in medical research elsewhere.